AVONEX adverse reactions1

The table below shows adverse reactions reported at an incidence of at least 2% greater frequency in AVONEX-treated patients than placebo-treated patients in placebo-controlled clinical trials.

Adverse reactions occurring ≥2% more frequently on AVONEX vs placebo1

Adverse reaction AVONEX n=351
%
Placebo n=333
%
Body as a Whole
Headache5855
Flu-like symptoms4929
Pain2321
Asthenia2418
Fever209
Chills195
Abdominal pain86
Injection site pain86
Infection74
Injection site inflammation62
Chest pain52
Injection site reaction31
Toothache31
Nervous System
Depression1814
Dizziness1412
Respiratory System
Upper respiratory tract infection1412
Sinusitis1412
Bronchitis85
Digestive System
Nausea2319
Musculoskeletal System
Myalgia2922
Arthralgia96
Urogenital
Urinary tract infection1715
Urine constituents abnormal30
Skin and Appendages
Alopecia42
Special Senses
Eye disorder42
Hemic and Lymphatic System
Injection site ecchymosis64
Anemia41
Cardiovascular System
Migraine53
Vasodilation20
Getting started

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One injection, once a week1

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AVONEX efficacy

Results in 3 key measures of relapsing MS disease activity

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