AVONEX dosing1

One injection, once a week for relapsing MS

AVONEX is a 30 mcg intramuscular injection that gives patients the flexibility to choose the day that works best for them.

AVONEX also offers patients the choice of 2 administration options:


AVONEX PEN is a prefilled, single-dose autoinjector that lets your patients treat their relapsing multiple sclerosis (MS) in a single click. It includes a covered needle that's half the length of the standard needle for AVONEX prefilled syringe. 

Download AVONEX PEN Instructions for Use
AVONEX prefilled syringe

AVONEX prefilled syringe lets your patients inject their weekly dose of AVONEX by following a step-by-step process.

Download AVONEX prefilled syringe Instructions for Use

AVONEX dosing and administration information

  • For intramuscular use only
  • Recommended dose: 30 mcg once a week
  • AVONEX may be titrated, starting with 7.5 mcg for first week, to reduce flu-like symptoms
  • Increase dose by 7.5 mcg each week for next 3 weeks until recommended dose of 30 mcg
  • First injection should be performed under the supervision of an appropriately qualified healthcare professional
  • If patients or caregivers are to administer AVONEX, train them in the proper intramuscular injection technique and assess their ability to inject intramuscularly to ensure the proper administration of AVONEX
  • Analgesics and/or antipyretics on treatment days may help ameliorate flu-like symptoms 

Advise your patients:

  • To rotate injection sites with each administration to minimize the likelihood of injection site reactions, including necrosis or localized infection
  • NOT to inject area of the body where the skin is irritated, reddened, bruised, infected, or scarred in any way
  • To check the injection site after 2 hours for redness, swelling, or tenderness
  • To contact their healthcare provider if they have a skin reaction and it does not clear up in a few days 

AVONEX doses per year

Watch the AVONEX injection video

AVONEX Injection training video

Show your patients how to prepare and give an injection with AVONEX PEN

Get Started

Get your patients started on therapy and enrolled in Biogen Support Services with the AVONEX Start Form.

E-Sign Start Form

Download Start Form
AVONEX efficacy

Results in 3 key measures of relapsing MS disease activity

See AVONEX efficacy
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Biogen Case Managers and Nurse Educators are here to help your patients start and continue on AVONEX

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